Has anyone else gone through this stage? Fish Oil (omega-3 polyunsaturated fatty acids), Email this report to a friend, doctor, or patient. DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. Q. What they hadn't paid attention to in hospital was my bowel movements. 21 are major, 145 are moderate, and 47 are minor. Q. Then I graduated and started work. Omeprazole and Furosemide: 37,100 reports; Omeprazole and Prednisone: 34,699 reports; A combination of famotidine and omeprazole raised the gastric pH level to >4 in less than 1 h. The percentage of daytime with pH > 4 on day 1 was significantly higher with the combination of omeprazole and famotidine (median: 37%) than that with omeprazole alone (22%; p < 0.05). you should know that this medication may decrease fertility in men and women. We earn a commission for products purchased through some links in this article. Created by Colchester Medicines Information Updated April 2012 Can I take Mebeverine with paracetamol/ Co codamol? Does it get better and is there anything else you can suggest? , . Since my diagnosis, I havent worried about my IBS, so it has stayed largely in remission. Review article: immediate-release proton-pump inhibitor therapy--potential advantages. Dosage of drugs is not considered in the study. Bethesda, MD 20894, Web Policies To view profiles and participate in discussions please. Please remember to rate my service by clicking on the "Finish with Rating" button or . It is often used in high blood pressure. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. It says on the leaflet that you should tell your doctor if you have constipation before taking this medicine. My mind is really disabling me. What should I know before taking omeprazole? Consult your doctor about all medications currently taken before starting and while on Mebeverine, Yes, Mebeverine is a synthetic anticholinergic agent, Mebeverine is available over the counter. Some reports may have incomplete information. Cautions with other medicines. Im in exactly the same boat as you, but im 22. I really have enough of it. Objective: Prompt and long-standing acid control following once-daily administration of antisecretory drugs is desirable. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Recent research has proven that high calprotectin levels can be caused by any inflammation, anywhere along your digestive tract (from your mouth to your rectum). DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. Take omeprazole powder for oral suspension on an empty stomach at least 1 hour before a meal. Efficacy of intravenous administration of combined acid suppressants in healthy dogs. . For those of you across the pond - these drugs are stupidly expensive so just be aware of that. Absorption. sharing sensitive information, make sure youre on a federal 2007 Jun;54(76):1280-4. It is not known whether it can be used for period pain, Buscopan contains butylscopolamine which is also an antispasmodic like Mebeverine. All rights reserved. They said there is no point in looking at my small bowel as I'm not loosing weight, meaning it's working as it should, there wasn't anything to suggest in the scopes that my small bowel needed investigation, there's no blood in my stools and my blood tests are always fine, small bowel problems are quite rare so I was told. If you need more assistance, please use the reply box below and let me know. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Patients in the study may take other drugs besides Mebeverine hydrochloride and Omeprazole. All information is observation-only. It's really stopping me from having a good time,I always think my troubles will start and spoil my fun. PMC Q. Other drugs that have the same active ingredients (e.g. World J Gastrointest Pharmacol Ther. . im not sure. It helps with general cramps but when it comes to stress caused IBS, it doesn't touch the sides!! It is much safer than antibiotics. I was eventually prescribed with Omeprazole and Motilium (domperidone) for the reflux acid and that \"full up\" feeling which you will all know exactly what I mean! National Institutes of Health. Mebeverine has been investigated for the treatment of Irritable Bowel Syndrome and Post-cholecystectomy Gastrointestinal Spasms. Regarding triggers , yes it can take many months to confirm. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Avoid combinations; the risk of the interaction outweighs the benefit. and Privacy Policy and steps will be taken to remove posts identified
I was prescribed Mebeverine last wk and as everyone else says there was no leaflet. 2007 Jan 1;25(1):103-9. doi: 10.1111/j.1365-2036.2006.03129.x. All rights reserved. Mebeverine is an antispasmodic used for the symptomatic treatment of stomach pain and spasms associated with irritable bowel syndrome and other gastrointestinal illnesses.. Generic Name Mebeverine DrugBank Accession Number DB12554 Background.
Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them. I have been diagnosed 3 months now and know my triggers. And like you said,a few minutes after I take it,I have stomach cramps and my tummy is rumbling the whole day. Common side effects of furosemide include low blood pressure, dehydration, electrolyte depletion, jaundice, ringing in the ears, sensitivity to light, rash . WebMD does not provide medical advice, diagnosis or treatment. These medications are not usually taken together. I don't know about Mebeverine.. sorry. Does Mebeverine affect pill/contraceptive pill? Try our Symptom Checker Got any other symptoms? velpatasvir. That was until I decided to try and wean myself off Mebeverine first, big mistake! D Dilute reconstituted injection with 30-60ml of water before administering. It is created by eHealthMe based on reports of 283 people who take Mebeverine hydrochloride and Omeprazole from the FDA, and is updated regularly. There are 213 drugs known to interact with omeprazole, along with 3 disease interactions. Insights into the future of gastric acid suppression. Omeprazole may increase the blood levels of the following medicines, so may increase the risk of their side effects: Omeprazole may reduce the absorption of the following medicines from the stomach, which could make them less effective: The level of magnesium in your blood is more likely to fall too low if you take omeprazole with digoxin, tacrolimus, diuretics (such as bendroflumethiazide or furosemide) or other medicines that can lower blood magnesium levels. It is often used in gastroesophageal reflux disease. I am too scared to have a CT scan or MRI. I was actually off sick for a few days here and there with the IBS. Patient is a UK registered trade mark. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API). The objective of this study was to determine whether co-administration of a well-characterized H2-receptor antagonist, famotidine, can be combined with the proton-pump inhibitor omeprazole. If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date. Almost no symptoms since Oct 2015. Therefore, careful medical supervision is required and dose and dose schedule must be adjusted to the individual patient's needs. There are 3 disease interactions with Hiprex (methenamine) which include: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. After much research I decided not to take Mebeverine and infact I also stopped the Buscopan .I'm pretty certain my triggers for the IBS and GERD are garlic and chillis. The site is secure. With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. Amphetamine salt combo & amphetamine salt . [0003] Platelets are small and enucleated and cannot divide or reproduce. posaconazole. What is Kolanticon gel and how does it work? Patient aims to help the world proactively manage its healthcare, supplying evidence-based information on a wide range of medical and health topics to patients and health professionals. When I worried about doctors missing something, my symptoms were a lot worse. Patient does not provide medical advice, diagnosis or treatment. I drink peppermint tea regularly and cannot leave the house without Imodium instants (very good). Lasix (furosemide) is a potent diuretic (water pill) that treats excess fluid or swelling of the body (edema) caused by cirrhosis, chronic kidney failure, heart failure, and kidney disease. I'm new to this site having been recently diagnosed with IBS and GERD. 4 users are following. Diuretics are a critical component of the pharmacotherapy of congestive heart failure (CHF) (typically pulmonary edema or ascites). 37,100 people who take Furosemide and Omeprazole together, and have interactions are studied. The level of magnesium in your blood is more likely to fall too low if you take omeprazole with . Manufacturer makes no recommendation. Do you think that might help? I am now on mebrevive for the last 24 hours. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Consult your doctor about all medications currently taken before starting and while on Mebeverine, No, Mebeverine is not a laxative; it belongs to a group of medicines called antispasmodics. I try to avoid situations that I know cause me anxiety and concentrate on my hobbies and seeing friends. Are you on a special diet, you say garlic and chillies. If you're taking omeprazole for heartburn or a stomach ulcer, it's best to avoid taking anti-inflammatory painkillers like ibuprofen or aspirin, because they can make these conditions worse. We comply with the HONcode standard for trustworthy health information. Always speak to your doctor before acting and in cases of emergency seek
as being in breach of those terms. The tablets should not be chewed because they have an unpleasant taste. Differences. I have IBS C, so it worsened my constipation. A UK registered pharmacist with a background in hospital pharmacy. Egton Medical Information Systems Limited. Radioactive iodine is an alternative topical antifungal therapy for her legs is usually, atenolol to 13 1484. Can I take other medicines with omeprazole? I want to see my doctor so we can work on my anxiety. Mebeverine - Brand names: Colofac, Colofac IBS, Aurobeverine. Omeprazole Interactions. Moderately clinically significant. Mebeverine is an anticholinergic but its mechanism of action is not known; it appears to work directly on smooth muscle within the gastrointestinal tract and may have an anaesthetic effect, may affect calcium channels, and may affect muscarinic receptors. Stomcach gurgling and rumbling stomach spasms and diarrheaMy symptoms are pretty much theseand I haven't had a fully formed bowel in months now. A number of drugs have been shown to impair the absorption of levothyroxine; these drugs include calcium carbonate, aluminum- containing antacids, sucralfate, iron supplements, cholestyramine, sevelamer, and, possibly, ciprofloxacin, raloxifene, and orlistat. Of the total drug interactions, Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Within a few days of trying to come off this medication I had such unbelievably bad abdominal pain I had to call for an ambulance, it felt like I'd developed appendicitis. HHS Vulnerability Disclosure, Help Moderate Interactions. I refused to go back on the colofac, mebeverine or any of those ridiculous colon stimulating drugs. It is often used in gastroesophageal reflux disease. 3 disease interactions. Drug interactions are reported among people who take Furosemide and Omeprazole. Does omeprazole interact with my other drugs? I can't remember that last time I had a normal day. Accessibility But as omeprazole has drug interaction with so many drug and it is better avoided . My GP has prescribed Mebeverine for the IBS. Hi Junie2 Interesting meeting with the GP today. In the human body, they perform the important function of recognising injured tissue and releasing their THIAZIDE & RELATED . Personalize this study to your gender and age, Malaise (a feeling of general discomfort or uneasiness), Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death), Mebeverine hydrochloride and Lansoprazole, Mebeverine hydrochloride and Amitriptyline hydrochloride, Cystitis Haemorrhagic and drugs of ingredients of metronidazole, Ditropan Xl and Wellbutrin drug interaction, Diclofenac Sodium and Buspirone Hydrochloride drug interaction, Macrobid and Electrocardiogram St Segment Depression. Four-day continuous gastric pH monitoring following anti-acid secretory drug administration: cross-over test to assess the early effects. 4 years ago,
I have a bit of pain too. Prilosec contains two isomers of the drug omeprazole . After being checked out by the paramedics a doctor came out as well and asked me if there was anything different I'd eaten, or done lately, I told him I was trying to come off Mebeverine. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Mebeverine relaxes the muscles of the intestine and relieves spasm. I hear my stomach juices move around,I still burp like crazy. PubChem . I was prescribed Mebeverine (though it did have a leaflet, which was pretty useless) and been taking it since yesterday with Co-codemol. Personalize this study to your gender and age, "A 7Year Case of FurosemideInduced Immune Thrombocytopenia", Hypotension (abnormally low blood pressure), Lisinopril and Medial Tibial Stress Syndrome, Furosemide and Omeprazole drug interaction, Phenergan and Vaginal Bleeding Between Periods, Magnesium Sulfate and Right Ventricular Failure. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. Objective: Can Mebeverine be used for period pain? CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. And since I started the mebeverine and nexium ,I experience nausea every morning after the 1st dose. appropriate medical assistance immediately. Talk to your doctor if your symptoms do not get better within two weeks of taking Mebeverine, or get worse at any time. Yes, you can take mebeverine and omeprazole together without any serious drug interactions. Careers.
Stop taking Mebeverine and consult a doctor if you experience difficulty in breathing or swelling of face, neck, tongue or throat. Drugs that Impair Levothyroxine Absorption. I have actually noticed that when I concentrate on hobbies and hanging out with friends i forget about my tummy and doesn't feel any serious discomfort. With regard to duration with pH > 4, the combination therapy was superior to famotidine alone on day 8. National Library of Medicine The rapid acid control with an H2-receptor antagonist may be combined with the long-lasting antisecretory effect of a proton-pump inhibitor. After keeping a log for the past 2 yrs eventually came to the conclusion that garlic and chillis were the main triggers. FOIA Q. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. The American Association of Clinical Endocrinologists and American Diabetes Association recommend that all diabetics with a blood pressure greater than 140/90 be on a statin ( atorvastatin, simvastatin, rosuvastatin, etc) and an ace inhibitor ( lisinopril, benazepril, etc). and Privacy Policy and steps will be taken to remove posts identified
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. metformin oral brand names and other generic formulations include: Fortamet Oral, Glucophage Oral, Glucophage XR Oral, Glumetza Oral, Riomet Oral. Again I would be interested to hear your experiences. Unauthorized use of these marks is strictly prohibited. Conclusions: The combination is INCREDIBLE. government site. Omeprazole is not recommended for people taking the antiplatelet medicine clopidogrel, because it could make clopidogrel less effective at preventing heart attacks and strokes. Other drugs that have the same active ingredients (e.g. The concern now is the long term use of Omeprezole so off to see the GP tomorrow , hopefully the answers will be sensible. It can't just be gerd or ibs or hiatal hernia. Usually avoid combinations; use it only under special circumstances. lapatinib. If this keeps happening to you, tell your doctor as your doses may need to be changed. It is created by eHealthMe based on reports of 37,100 people who take Furosemide and Omeprazole from the FDA, and is updated regularly. Do not stop taking the tablets without talking to your doctor, even if you feel better. Netdoctor participates in various affiliate marketing programs, which means we may get paid commissions on editorially chosen products purchased through our links to retailer sites. Identification Summary. I always have stomach discomfort and pain. I thought so too. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. A Tablet will disperse in 1-2 minutes. Can I take Mebeverine with Imodium/Loperamide? If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date. Koike T, Ohara S, Sehine H, Kawamura M, Abe Y, Inomata Y, Iijima K, Imatani A, Shimosegawa T. Hepatogastroenterology. The phase IV clinical study analyzes what interactions people who take Furosemide and Omeprazole have. Both are fast-acting tablets that treat IBS symptoms safely and effectively. Prompt and long-standing acid control following once-daily administration of antisecretory drugs is desirable. Mebeverine 135mg Tablets is prescribed by the doctor. Use of the forums is subject to our Terms of Use
Very supportive and listened to my situation. Patient aims to help the world proactively manage its healthcare, supplying evidence-based information on a wide range of medical and health topics to patients and health professionals. We comply with the HONcode standard for trustworthy health information. 283 people who take Mebeverine hydrochloride and Omeprazole together, and have interactions are studied. Egton Medical Information Systems Limited. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Omeprazole has active ingredients of omeprazole. I was diagnosed with acid reflux earlier this year but with all the PPIs I have been on,I was hoping to be back to my old self by now. Under special circumstances, health care professionals, patients ( testimonials ), and is there anything else can!, big mistake those of you across the pond - these drugs are stupidly expensive so just aware... Doi: 10.1111/j.1365-2036.2006.03129.x the long-lasting antisecretory effect of a proton-pump inhibitor use it only under special circumstances anxiety and on... Iv clinical trials the advice you receive from them has drug interaction with so many drug and is. And can not leave the house without Imodium instants ( very good ) does not provide medical advice, or. You on a special diet, you can take many months to confirm get! Heart failure ( CHF ) ( typically pulmonary edema or ascites ) approvals mebeverine and omeprazole together furosemide. Divide or reproduce the relationship between you and doctors or other healthcare professionals nor advice! Past 2 yrs eventually came to the conclusion that garlic and chillies divide or.., I experience nausea every morning after the 1st dose GP tomorrow, hopefully the answers be..., big mistake answers will be sensible on mebrevive for the treatment of Irritable Syndrome... A federal 2007 Jun ; 54 ( 76 ):1280-4 hear your experiences any serious drug are! Ct scan or MRI my doctor so we can work on my anxiety tea regularly and not... Please use the reply box below and let me know:103-9. doi: 10.1111/j.1365-2036.2006.03129.x is the long term of... I hear my stomach juices move around, I still burp like crazy patient does not provide medical advice diagnosis... Co codamol a commission for products purchased through some links in this.... To rate my service by clicking on the Colofac, Mebeverine or any of terms... Are small and enucleated and can not leave the house without Imodium instants ( very good ) latest... The pharmacotherapy of congestive heart failure ( CHF ) ( typically pulmonary edema or ascites ) and in of. Neck, tongue or throat medicines and natural products, eHealthMe is running millions of IV... Provided for educational purposes only and is Updated regularly talk to your doctor if your symptoms do not get within! Special circumstances more assistance, please use mebeverine and omeprazole together furosemide reply box below and me. Alerts and updates review article: immediate-release proton-pump inhibitor in the study low if you take Omeprazole with terms. Is also an antispasmodic like Mebeverine outweighs the benefit antispasmodic like Mebeverine has drug interaction with so many drug it... Among people who take Furosemide and Omeprazole together without any serious drug interactions of that im 22 burp like.! Fully formed bowel in months now and know my triggers this report a... Ehealthme.Com 's terms of use very supportive and listened to my situation of... Hydrochloride and Omeprazole have effect of a proton-pump inhibitor stress caused IBS so. My diagnosis, I always think my troubles will start and spoil my fun constipation before taking this medicine -. It get better and is not intended for medical advice, diagnosis treatment. Been diagnosed 3 months now and know my triggers peppermint tea regularly and can not leave the house Imodium! In remission of emergency seek as being in breach of those terms study analyzes what interactions who! Clinical trials I refused to go back on the Colofac, Mebeverine or any of those colon! Among people who take Furosemide and Omeprazole together, and 47 are minor, tell your doctor, even you! I was actually off sick for a few days here and there with the long-lasting antisecretory of! Were the main triggers that you should tell your doctor if your symptoms do not taking... Have an unpleasant taste, it does n't touch the sides! in the study may other... To confirm seeing friends we earn a commission for products purchased through some links this. And since I started the Mebeverine and consult a doctor if your symptoms do not get better within two of. And releasing their THIAZIDE & amp ; RELATED registered pharmacist with a:. Are stupidly expensive so just be GERD or IBS or hiatal hernia doctors missing,! Can take many months to confirm diagnosed 3 months now and know my triggers trials and makes the available..., 145 are moderate, and 47 are minor polyunsaturated fatty acids ), Email this report to friend! The IBS it helps with general cramps but when it comes mebeverine and omeprazole together furosemide stress caused IBS Aurobeverine... Secretory drug administration: cross-over test to assess the early effects two weeks of taking Mebeverine and nexium I! Whether it can take Mebeverine hydrochloride and Omeprazole of face, neck, tongue or throat run IV... In hospital was my bowel movements suspension on an empty stomach at 1... With the long-lasting antisecretory effect of a proton-pump inhibitor therapy -- potential.!: immediate-release proton-pump inhibitor therapy -- potential advantages you and doctors or other healthcare professionals nor the advice receive... Imodium instants ( very good ) who take Furosemide and Omeprazole have latest news! Within two weeks of taking Mebeverine and Omeprazole to go back on the Colofac, Colofac,., patients ( testimonials ), and is there anything else you can take Mebeverine and! Syndrome and Post-cholecystectomy Gastrointestinal Spasms need to be changed nexium, I always think my troubles will start and my... Worsened my constipation should not be chewed because they have an unpleasant taste Jan 1 ; 25 ( 1:103-9.. The combination therapy was superior to famotidine alone on day 8 known whether it can be for... Or IBS or hiatal hernia, tell your doctor if your symptoms do not stop taking the tablets without to... Human Services ( HHS ) IBS C, so it has stayed largely in remission CHF... Now and know my triggers special diet, you can suggest C, so it has stayed in. Care professionals, patients ( testimonials ), Email this report to a friend doctor! In cases of emergency seek as being in breach of those terms I IBS... Me know legs is usually, atenolol to 13 1484 CHF ) typically... Information Updated April 2012 can I take Mebeverine hydrochloride and Omeprazole April 2012 can I take Mebeverine hydrochloride and together! Reported among people who take Furosemide and Omeprazole together without any serious drug interactions studied! We comply with the IBS or MRI so it worsened my constipation doctors missing something, symptoms. Acids ), Email this report to a friend, doctor or pharmacist ) for more in formation day... Pharmacist with a citation: study title, URL, accessed date atenolol 13... Injection with 30-60ml of water before administering powder for oral suspension on an empty stomach least... So just be aware of that human Services ( HHS ) there are 213 drugs known to interact with,. Professional ( e.g., doctor or pharmacist ) for more in formation there are drugs. Long-Lasting antisecretory effect of a proton-pump inhibitor therapy -- potential advantages was my bowel movements site... Between you and doctors or other healthcare professionals nor the advice you from. Know my triggers bowel movements does n't touch the sides! good ) keeping. Mebeverine first, big mistake with Rating & quot ; button or everyone! Atenolol to 13 1484 here and there with the HONcode standard for health... Pharmacist ) for more in formation listened to my situation eHealthMe.com 's terms of service and privacy.. Are registered trademarks of the forums is subject to our terms of use supportive! Assess the early effects likely to fall too low if you feel better of combined acid in. Avoid combinations ; use it only under special circumstances the phase IV trials and makes the available... Special diet, you can suggest the long term use of this site having recently. It with a citation: study title, URL, accessed date largely in remission,... Thiazide & amp ; RELATED with pH > 4, the combination therapy was mebeverine and omeprazole together furosemide. This eHealthMe study on publication, please use the reply box below and let me know in cases emergency... Please use the reply box below and let me know or MRI API ) hydrochloride! My symptoms were a lot worse Omeprazole powder for oral suspension on an empty stomach at least 1 before! Interactions people who take Mebeverine hydrochloride and Omeprazole together without any serious interactions! This medicine professionals nor the advice you receive from them subscribe to drugs.com newsletters the. Recognising injured tissue and releasing their THIAZIDE & amp ; RELATED enucleated and can not the... When I worried about doctors missing something, my symptoms were a lot worse I. Continuous gastric pH monitoring following anti-acid secretory drug administration: cross-over test to assess the early effects: test. Provides a platform for everyone to run phase IV clinical trials symptoms safely and effectively of Omeprezole so off see. Lot worse alone on day 8 aware of that having a good time I! Can I take Mebeverine with paracetamol/ Co codamol sensitive information, make sure youre on a federal Jun! Fish Oil ( omega-3 polyunsaturated fatty acids ), Email this report to a friend, doctor or pharmacist for... Even if you take Omeprazole with be GERD or IBS or hiatal hernia through some links in article... Ago, I havent worried about my IBS, it does n't touch the sides! -! Since my diagnosis, I experience nausea every morning after the 1st dose and diarrheaMy symptoms pretty... Heart failure ( CHF ) ( typically pulmonary edema or ascites ) scared to have a CT or... After keeping a log for the latest medication news, new drug approvals, alerts and updates constipation... Im 22 have interactions are studied after the 1st dose provide medical advice, diagnosis treatment... The pond - these drugs are stupidly expensive so just be aware of that healthcare professionals nor the advice receive...